Anaphylactic Shock to a DEET-Containing Insect Repellent

Severe allergic reaction to diethyltoluamide (DEET) containing insect repellent

Case presentation A 53 year-old female bridge inspector presented with allergic reaction to diethyltoluamide (DEET) containing insect repellent. She had prior use without difficulty. In 2013, she used the insect repellent and with only a small amount making contact with her forehead, she had immediate pruritus and erythema on her forehead, persisting for an hour. The following week, she used a ...

Insect odorant receptors are molecular targets of the insect repellent DEET.

DEET (N,N-diethyl-meta-toluamide) is the world's most widely used topical insect repellent, with broad effectiveness against most insects. Its mechanism of action and molecular target remain unknown. Here, we show that DEET blocks electrophysiological responses of olfactory sensory neurons to attractive odors in Anopheles gambiae and Drosophila melanogaster. DEET inhibits behavioral attraction ...

The Repellent DEET Potentiates Carbamate Effects via Insect Muscarinic Receptor Interactions: An Alternative Strategy to Control Insect Vector-Borne Diseases

Insect vector-borne diseases remain one of the principal causes of human mortality. In addition to conventional measures of insect control, repellents continue to be the mainstay for personal protection. Because of the increasing pyrethroid-resistant mosquito populations, alternative strategies to reconstitute pyrethroid repellency and knock-down effects have been proposed by mixing the repelle...

Anaphylactic shock to raspberry.

Seizures temporally associated with use of DEET insect repellent--New York and Connecticut.

In August 1989, epidemiologists from the New York State Department of Health (NYSDH) investigated five reports of generalized seizures temporally associated with topical use of N,Ndiethyl-m-toluamide (DEET). Three of the case-patients, one from New York and two from Connecticut, were reported by a pediatric neurologist who practices in both states. One case was reported initially to an entomolo...